CNN Turk quoted Turkish foreign ministry undersecretary Feridun Sinirlioglu as saying the countries had agreed to create a 98-kilometre long and 45-kilometre wide area to be patrolled by members of the opposition Free Syrian Army.
In a later statement,Turkey's foreign ministry quoted Mr Sinirlioglu as saying:"The control and protection of this region cleared of[Islamic State] will be conducted by Syrian opposition forces and the necessary air defence and support for this ... will be provided by the United States and Turkey."
Asked about the report,however,US State Department spokesman Mark Toner said:"There's no agreement on some kind of zone."
Mr Toner said he had not seen the Turkish official's remarks and could not address them."I'm not denying his claims,"he added.
"We've been pretty clear from the podium and elsewhere saying there's no zone,no safe haven,we're not talking about that here. What we're talking about is a sustained effort to drive ISIL out of the region,"Mr Toner told a news briefing.