The clubs have sought assistance from Football Federation Australia - who have,in turn,canvassed the views of fellow associations in Japan,South Korea and China - while the unions representing both players and coaches have also been engaged to help navigate a complicated political landscape.
Professional Footballers Australia co-CEO Beau Busch said the AFC Champions League was"hugely respected"by all players as the pinnacle of club football in Asia.
"However,what is being asked of the players,staff and the clubs to participate in the ACL in Qatar is immense and has the potential to have a significant impact on their health and wellbeing and undermine their preparations ahead of the 2020-21 A-League Season,"Busch said.
"We will continue to work with the clubs,FFA and FIFPro on a reasonable solution."
The issues are primarily based on the possibility of exposure to COVID-19 in Qatar,which is currently recording around 200-300 new cases per day.
During last month's West Zone fixtures,defending AFC Champions League winners Al-Hilal were effectively kicked out of the competition after an outbreak of COVID-19 within their squad,despite having fully observed the AFC's protocols while in Doha.