One protester was seen waving an Australian flag upside down and another held aloft a Eureka flag,while the action prompted the next-door Queensland Parliament to lock its gates.
The group stopped outside 1 William Street hoping to speak to Premier Annastacia Palaszczuk and booed when it became clear she would not meet with the crowd,before chants of “you serve us”.
Members of the group insisted they would not move on until someone came down from 1 William Street to accept a statement from their leader.
Some protesters had earlier clambered onto the Parliament fence as others shouted:“stop protecting the paedophiles”.
The crowd held signs rejecting “medical apartheid” and “coercion”.
Police were at one stage forced to step in between elements of the crowd and a Seven News crew who were cornered,with protesters singling out the team amid shouts of “tell the truth”.