Detectives from the Major Collision Investigation Unit believe a Holden station wagon was travelling inbound at speed in the emergency lanes on the Monash Freeway at Narre Warren,when it clipped a truck and lost control about 7.30am.
A male passenger in the station wagon was taken to hospital where he remains in a stable condition.
Police arrested the 21-year-old driver at the scene and have charged him with negligently causing serious injury,dangerous driving causing serious injury,conduct endangering life,conduct endangering serious injury,driving at a dangerous speed and driving in a dangerous manner.
He was also charged with refusing a preliminary oral fluid test,refusing evidentiary breath test and refusing a blood sample.
The Monash Freeway inbound was closed to all traffic at Ernst Wanke Road throughout the morning causing lengthy delays before it was re-opened to all traffic after 1pm.