A perfect hat-trick from Olivier Giroud helped Chelsea overcome Dynamo Kiev 5-0 and cruise into the Europa League quarter-finals.
Arsenal took an early lead but a red card for Sokratis Papastathopoulos changed the game as the Gunners slumped to a 3-1 defeat at Rennes.
Arsenal beat BATE Borisov 3-0 to reach the Europa League last 16.
Arsenal have suffered a surprise 1-0 loss at Bate Borisov in the first leg of their Europa League last-32 clash,with London rivals Chelsea winning 2-1 at Malmo.
Chelsea have condemned supporters who were heard singing an anti-Semitic chant in Hungary,just days after four fans were suspended for abusing Raheem Sterling.
Rangers'dreams of reaching the Europa League last 32 were extinguished as they failed to get the victory they needed to edge out Rapid Vienna.
Arsenal have secured top spot in Europa League group E after a comfortable 3-0 victory over Vorskla Poltava in Kiev.
UEFA has said Arsenal's match with Vorskla Poltava will go ahead despite the president of Ukraine imposing martial law as tensions with Russia escalate.
Chelsea are through to the knockout stages of the Europa League with a goal from striker Oliver Giroud securing a 1-0 win over BATE Borisov.